Sugi Predict

Sugi Predict / Compounds / SCHEMBL2649233

SCHEMBL2649233

SCHEMBL2649233

O=C(O)c1ccc(CO)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A1 P22736 1/20 0.50
▸ NR4A2 P43354 1/20 0.50
▸ NR4A3 Q92570 1/20 0.50
▸ HMGB1 P09429 1/20 0.50
▸ CXCL12 P48061 1/20 0.50
▸ WDR5 P61964 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ CYP2C9 P11712 2/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ LDHA P00338 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ ALOX12 P18054 1/20 0.46
▸ ATIC P31939 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ HIF1A Q16665 1/20 0.45
▸ ACE2 Q9BYF1 2/20 0.42
▸ THRB P10828 1/20 0.41
▸ FOLH1 Q04609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21585556 0.88 NR4A1 (0.55) NR4A1NR4A2NR4A3HMGB1CXCL12
SCHEMBL6323290 0.86 CNR2 (0.50) NR4A1NR4A2NR4A3HMGB1CXCL12
Ethylene Glycol SCHEMBL27585251 0.85 NR4A1 (0.56) NR4A1NR4A2NR4A3HMGB1CXCL12
SCHEMBL30838412 0.84 NR4A1 (0.65) NR4A1NR4A2NR4A3HMGB1WDR5
SCHEMBL30838413 0.84 NR4A1 (0.65) NR4A1NR4A2NR4A3HMGB1WDR5
SCHEMBL29406630 0.84 NR4A1 (0.65) NR4A1NR4A2NR4A3HMGB1WDR5
SCHEMBL28798 0.84 NR4A1 (0.65) NR4A1NR4A2NR4A3HMGB1WDR5
SCHEMBL17537563 0.84 TDP1 (0.56) NR4A1NR4A2NR4A3HMGB1CXCL12
SCHEMBL13749032 0.84 HMGB1 (0.47) NR4A1NR4A2NR4A3HMGB1CXCL12
SCHEMBL5500921 0.84 HMGB1 (0.47) NR4A1NR4A2NR4A3HMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970921-B High-water-reduction low-sensitivity polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2020-07-03 — — CN claimed
CN-105435811-A 1,4-cyclohexanedimethanol catalyst and preparation method thereof CHINA PETROLEUM & CHEM CORP 2016-03-30 — — CN claimed
CN-118146085-A Treatment method for material ending in middle of reaction for preparing 1, 4-naphthalene dicarboxylic acid by oxidizing 1-methyl-4-naphthalene carboxylic acid by oxygen 黄石市利福达医药化工有限公司 2024-06-07 — — CN disclosed
CN-114014750-B Method for separating and purifying 1, 4-naphthalene dicarboxylic acid from distillation residues of 1, 4-naphthalene dicarboxylic acid reaction mother liquor 黄石市利福达医药化工有限公司 2024-02-13 — — CN disclosed
CN-113336640-B Method for reducing content of 1, 4-naphthalenedicarboxylic acid impurities 黄石市利福达医药化工有限公司 2022-04-26 — — CN disclosed
CN-114014750-A Method for separating and purifying 1, 4-naphthalenedicarboxylic acid from distillation residue of 1, 4-naphthalenedicarboxylic acid reaction mother liquor 黄石市利福达医药化工有限公司 2022-02-08 — — CN disclosed
CN-111848947-B Naphthalene ring-based precise self-degradation amphiphilic block oligomer, and synthesis method and application thereof 中国科学技术大学 2021-10-01 — — CN disclosed
CN-113336640-A Method for reducing content of 1, 4-naphthalenedicarboxylic acid impurities 黄石市利福达医药化工有限公司 2021-09-03 — — CN disclosed
CN-112679338-A Method for preparing oxazoline insecticide alfilana intermediate 丽珠集团新北江制药股份有限公司 2021-04-20 — — CN disclosed
CN-111848947-A Naphthalene ring-based precise self-degradation amphiphilic block oligomer, and synthesis method and application thereof 中国科学技术大学 2020-10-30 — — CN disclosed
CN-109970921-B High-water-reduction low-sensitivity polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2020-07-03 — — CN disclosed
CN-101278211-A Optical composite material and optical element CANON KK (JP) 2008-10-01 — — CN disclosed
CN-101277997-A Method for producing cellulose ester film, polarizing plate, and liquid crystal display device KONICA MINOLTA OPTO INC (JP) 2008-10-01 — — CN disclosed
US-6982348-B2 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-01-03 — — US disclosed
US-20040127574-A1 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-07-01 — — US disclosed
EP-1362846-A1 AMINOETHANOL DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2003-11-19 — — EP disclosed
US-6613942-B1 Nonpeptide; 4-hydroxy benzoic acid hydrazides NOVO NORDISK A/S (DK) 2003-09-02 — — US disclosed
EP-0994848-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-04-26 — — EP disclosed
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 — — WO disclosed
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127574-A1 Aminoethanol derivatives CETP, LCAT, MTTP NR4A1 595/4885NR4A2 649/4885NR4A3 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.