Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | USP7 | Q93009 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2047618 | 0.87 | ACHE (0.42) | HTR2CCHRNB2CHRNA4SLC6A2SLC6A4 | |
| SCHEMBL31131399 | 0.86 | HTR2C (0.58) | HTR2CCHRNB2CHRNA4QDPRGABRA1 | |
| SCHEMBL19347098 | 0.86 | HTR2C (0.58) | HTR2CCHRNB2CHRNA4QDPRGABRA1 | |
| Hydrochloric Acid SCHEMBL25328473 | 0.84 | HTR2C (0.59) | HTR2CCHRNB2CHRNA4QDPRGABRA1 | |
| Hydrochloric Acid SCHEMBL30493296 | 0.84 | HTR2C (0.59) | HTR2CCHRNB2CHRNA4QDPRGABRA1 | |
| SCHEMBL8313932 | 0.81 | QDPR (0.55) | HTR2CCHRNB2CHRNA4QDPRUSP7 | |
| SCHEMBL17948231 | 0.81 | HTR2C (0.61) | HTR2CCHRNB2CHRNA4GABRA1GABRB2 | |
| SCHEMBL9785240 | 0.81 | PTGDR2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL19956276 | 0.80 | PLG (0.40) | HTR2CCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4888125 | 0.80 | HTR2C (0.62) | HTR2CCHRNB2CHRNA4GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |