Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NRP1 | O14786 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24605064 | 0.84 | HPRT1 (0.40) | HTR1BHTR2BGPR65HPRT1ALDH1A1 | |
| SCHEMBL24605003 | 0.84 | HPRT1 (0.40) | HTR1BHTR2BGPR65HPRT1ALDH1A1 | |
| SCHEMBL30366540 | 0.83 | HPRT1 (0.46) | HTR1BHTR2BGPR65HPRT1SLC6A4 | |
| SCHEMBL6562728 | 0.83 | HPRT1 (0.46) | HTR1BHTR2BGPR65HPRT1SLC6A4 | |
| SCHEMBL24605123 | 0.81 | CYP1A2 (0.46) | HTR1BHTR2BGPR65HPRT1ALDH1A1 | |
| SCHEMBL29587482 | 0.80 | CYP1A2 (0.41) | HTR1BHTR2BGPR65ALDH1A1TSHR | |
| SCHEMBL631743 | 0.80 | CYP1A2 (0.41) | HTR1BHTR2BGPR65ALDH1A1TSHR | |
| SCHEMBL24605215 | 0.80 | HPRT1 (0.37) | HTR1BHTR2BGPR65HPRT1ALDH1A1 | |
| SCHEMBL24605244 | 0.78 | HPRT1 (0.36) | HTR1BHTR2BGPR65HPRT1CYP1A2 | |
| SCHEMBL24605407 | 0.78 | HPRT1 (0.36) | HTR1BHTR2BGPR65HPRT1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963459-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |
| US-20080303422-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20080303422-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |