SCHEMBL1374979

SCHEMBL1374979

CC(=O)C(N=Nc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.47
KDM4E B2RXH2 3/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
LMNA P02545 1/20 0.46
ALDH1A1 P00352 7/20 0.43
THRB P10828 1/20 0.43
RAB9A P51151 1/20 0.43
BCL6 P41182 1/20 0.41
BCOR Q6W2J9 1/20 0.41
KLK7 P49862 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PKM P14618 1/20 0.40
GAA P10253 1/20 0.40
XDH P47989 1/20 0.40
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NOS1 P29475 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1374976 1.00 MAPT (0.47) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL1374982 1.00 MAPT (0.47) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL16326827 0.95 BCL6 (0.45) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL16330289 0.95 BCL6 (0.45) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL16326753 0.94 MAPT (0.46) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL28900433 0.92 BCL6 (0.45) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL21655355 0.88 MAPT (0.48) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL23786268 0.88 MAPT (0.47) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL12014052 0.88 MAPT (0.47) MAPTKDM4ETP53MAPK1MEN1
SCHEMBL16326754 0.87 MAPT (0.44) MAPTKDM4ETP53MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577368-B2 Opaque polyester-based materials HOLLAND COLOURS N.V. (NL) 2026-03-17 US claimed
US-20220282060-A1 OPAQUE POLYESTER-BASED MATERIALS HOLLAND COLOURS N.V. (NL) 2022-09-08 US claimed
EP-3983195-A1 OPAQUE POLYESTER-BASED MATERIALS Holland Colours N. V. (NL) 2022-04-20 EP claimed
CN-114127189-A Lightproof polyester-based materials 荷兰颜料股份有限公司 2022-03-01 CN claimed
JP-10114374-A None JP disclosed
US-12577368-B2 Opaque polyester-based materials HOLLAND COLOURS N.V. (NL) 2026-03-17 US disclosed
WO-2025136104-A1 BIO-SOURCED PHTHALOCYANINE COMPLEX, PREPARATION AND USE THEREOF HOLLAND COLOURS N.V. (NL) 2025-06-26 WO disclosed
EP-4574911-A1 BIO-SOURCED PHTHALOCYANINE COMPLEX, PREPARATION AND USE THEREOF Holland Colours N. V. (NL) 2025-06-25 EP disclosed
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 EP disclosed
US-20220282060-A1 OPAQUE POLYESTER-BASED MATERIALS HOLLAND COLOURS N.V. (NL) 2022-09-08 US disclosed
US-11324688-B2 Bicomponent composition WELLA INTERNATIONAL OPERATIONS SWI (CH) 2022-05-10 US disclosed
US-8563107-B2 Container for medical products DAIKYO SEIKO, LTD. (JP) 2013-10-22 US disclosed
US-8367823-B2 Colorants based N-halamines compositions and method of making and using BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-02-05 US disclosed
US-20110284559-A1 CONTAINER FOR MEDICAL PRODUCTS DAIKYO SEIKO, LTD. (JP) 2011-11-24 US disclosed
CN-101868506-A Colorants based N-halamines compositions and method of making and using UNIV TEXAS 2010-10-20 CN disclosed
EP-2201069-A2 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING Board of Regents, The University of Texas System (US) 2010-06-30 EP disclosed
WO-2009039180-A2 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-03-26 WO disclosed
US-20090074825-A1 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-03-19 US disclosed
JP-H10114374-A CONTAINER FOR SANITARY ARTICLE DAIKYO SEIKO:KK 1998-05-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577368-B2 Opaque polyester-based materials STRA6, RICTOR, RPL35 MAPT 2046/4885KDM4E 3442/4885TP53 1919/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK MAPT 621/4885KDM4E 746/4885TP53 1338/4885
US-20090074825-A1 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING TYR, MPO, NISCH MAPT 3260/4885KDM4E 2094/4885TP53 3051/4885
US-11324688-B2 Bicomponent composition KRT18, EXOSC10, EXOSC9 MAPT 1247/4885KDM4E 1673/4885TP53 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.