Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | LHCGR | P22888 | 11/20 | 0.64 |
| ▸ | FSHR | P23945 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327464 | 0.91 | TSHR (0.82) | TSHRLHCGRFSHRCHRM4MEN1 | |
| SCHEMBL4327472 | 0.91 | TSHR (0.82) | TSHRLHCGRFSHRCHRM4MEN1 | |
| SCHEMBL13749858 | 0.88 | TSHR (0.79) | TSHRLHCGRFSHRCHRM4MEN1 | |
| SCHEMBL13757312 | 0.88 | TSHR (0.79) | TSHRLHCGRFSHRCHRM4BRAF | |
| SCHEMBL4325936 | 0.82 | LHCGR (0.71) | TSHRLHCGRFSHRCHRM4BRAF | |
| SCHEMBL4326072 | 0.78 | LHCGR (1.00) | TSHRLHCGRFSHRCHRM4MEN1 | |
| SCHEMBL32156160 | 0.78 | LHCGR (1.00) | TSHRLHCGRFSHRCHRM4MEN1 | |
| SCHEMBL4421168 | 0.77 | LHCGR (0.84) | TSHRLHCGRFSHRCHRM4BRAF | |
| SCHEMBL4315364 | 0.76 | LHCGR (1.00) | TSHRLHCGRFSHRCHRM4BRAF | |
| SCHEMBL4425902 | 0.75 | LHCGR (0.78) | TSHRLHCGRFSHRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203716-A1 | Pyrimidine low molecular weight ligands for modulating hormone receptors | The Government of the United States of America as represented by the Secretary of the | 2009-08-13 | — | — | US | disclosed |
| US-20090203716-A1 | Pyrimidine low molecular weight ligands for modulating hormone receptors | The Government of the United States of America as represented by the Secretary of the | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203716-A1 | Pyrimidine low molecular weight ligands for modulating hormone receptors | FSHR, TSHR, TRHR | TSHR 2/4885LHCGR 5/4885FSHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.