Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751991 | 0.88 | CCR6 (0.46) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24821066 | 0.83 | CCR6 (0.54) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11928331 | 0.82 | CCR6 (0.49) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14476880 | 0.82 | CCR6 (0.63) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL25245639 | 0.82 | CCR6 (0.41) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11305822 | 0.81 | CCR6 (0.51) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL25209279 | 0.81 | L3MBTL1 (0.40) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL18057682 | 0.80 | CCR6 (0.60) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9942494 | 0.80 | CCR6 (0.57) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL25628629 | 0.80 | CCR6 (0.64) | CCR6PAX8ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209585-A1 | CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF THE DERIVATIVES, AND USE OF THE SAME | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209585-A1 | CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF THE DERIVATIVES, AND USE OF THE SAME | SQLE, FDFT1, PTGIS | CCR6 791/4885PAX8 3204/4885ALDH1A1 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.