Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614177 | 0.86 | POLB (0.47) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL13753083 | 0.85 | BRD4 (0.46) | POLBL3MBTL1KMT2ATSHRHTT | |
| SCHEMBL27344771 | 0.82 | ALDH1A1 (0.58) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL13753140 | 0.81 | L3MBTL1 (0.54) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL13753137 | 0.81 | L3MBTL1 (0.54) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL12121132 | 0.80 | POLB (0.53) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL14547928 | 0.78 | POLB (0.51) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL582871 | 0.78 | TMEM97 (0.57) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL21351181 | 0.78 | L3MBTL1 (0.56) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL28460519 | 0.78 | POLB (0.72) | POLBL3MBTL1THRBRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |