SCHEMBL13753271

SCHEMBL13753271

Bc1ccc2c3c(ccc(Br)c13)C(=O)OC2=O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYMS P04818 4/20 0.41
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502543 0.86 TYMS (0.48) TYMSALOX15TDP1MEN1POLB
SCHEMBL13753481 0.84 S100A4 (0.38) MEN1POLBKMT2AALDH1A1
SCHEMBL148025 0.76 TYMS (0.62) TYMSALOX15TDP1MEN1POLB
SCHEMBL9111658 0.74 TYMS (0.50) TYMSALOX15TDP1MEN1POLB
SCHEMBL14399549 0.72 TYMS (0.63) TYMSALOX15TDP1MEN1POLB
SCHEMBL14290229 0.72 TYMS (0.35) TYMSALOX15TDP1
SCHEMBL29362967 0.71 TYMS (0.61) TYMSMEN1POLBKMT2AALDH1A1
SCHEMBL320954 0.71 TYMS (0.61) TYMSMEN1POLBKMT2AALDH1A1
SCHEMBL200283 0.70 TYMS (0.47) TYMSMEN1POLBKMT2AALDH1A1
SCHEMBL128103 0.69 TYMS (0.41) TYMSALOX15TDP1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085766-A2 Method for identifying electrophiles and nucleophiles in a sample Technion Research and Development Foundation, Ltd. (IL) 2009-08-05 EP disclosed