Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760366 | 0.85 | NPC1 (0.55) | TRPV1MCHR1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL13753069 | 0.82 | EPHX2 (0.63) | TRPV1EPHX2NR1H4PPARGPPARA | |
| SCHEMBL11448795 | 0.79 | ALDH1A1 (0.51) | TRPV1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL10294117 | 0.77 | EPHX2 (0.50) | EPHX2NR1H4PPARGPPARAALDH1A1 | |
| SCHEMBL10740417 | 0.77 | ALDH1A1 (0.53) | TRPV1EPHX2HTTPPARGPPARA | |
| SCHEMBL13754120 | 0.76 | TP53 (0.51) | HTTMCHR1ALDH1A1TSHRLMNA | |
| SCHEMBL24190676 | 0.76 | HTT (0.72) | EPHX2HTTHDAC4HDAC6ALDH1A1 | |
| SCHEMBL11757405 | 0.74 | NPC1 (0.59) | TRPV1MCHR1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9687321 | 0.74 | LMNA (0.54) | TRPV1EPHX2HTTALDH1A1LMNA | |
| SCHEMBL10664357 | 0.73 | TRPV1 (0.61) | TRPV1HTTALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |