SCHEMBL13754141

SCHEMBL13754141

CCCOc1ccc(C(=O)C(OCC(C)Cc2ccc(C(C)(C)C)cc2)OCC(C)Cc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
ACACB O00763 3/20 0.44
NR1H4 Q96RI1 3/20 0.44
EPHX2 P34913 2/20 0.44
PLK1 P53350 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 2/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456979 0.93 PPARG (0.47) NR4A2RXRARXRBACACBNR1H4
SCHEMBL13754142 0.90 ACACB (0.45) NR4A2RXRARXRBACACBNR1H4
SCHEMBL13754138 0.86 NR1H4 (0.52) NR4A2RXRARXRBNR1H4EPHX2
SCHEMBL13754136 0.83 ESRRG (0.45) NR4A2RXRARXRBACACBLMNA
SCHEMBL4445520 0.81 MEN1 (0.41) ACACBNR1H4LMNAMAPTSMN1; SMN2
SCHEMBL13754143 0.81 NR1H4 (0.51) NR4A2RXRARXRBACACBNR1H4
SCHEMBL13754176 0.80 ESRRG (0.44) NR4A2NR1H4EPHX2LMNAL3MBTL1
SCHEMBL13754134 0.79 PIN1 (0.40) NR4A2RXRARXRBACACBNR1H4
SCHEMBL13754169 0.78 NR1H4 (0.45) NR1H4EPHX2LMNAL3MBTL1MAPT
SCHEMBL13754166 0.77 MEN1 (0.47) ACACBNR1H4LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572938-B2 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2009-08-11 US disclosed
US-7572938-B2 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2009-08-11 US disclosed