SCHEMBL13754166

SCHEMBL13754166

COc1ccc(C(=O)C(OCC(C)Cc2ccc(C(C)(C)C)cc2)OCC(C)Cc2ccc(C(C)(C)C)cc2)cc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
PPARG P37231 1/20 0.42
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
LDHA P00338 1/20 0.40
ACACB O00763 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MAPK1 P28482 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13754138 0.85 NR1H4 (0.52) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL13754134 0.82 PIN1 (0.40) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL13754136 0.81 ESRRG (0.45) MEN1KMT2AALDH1A1LMNAACACB
SCHEMBL4451298 0.80 ADRB2 (0.42) MEN1KMT2AALDH1A1LMNAMAPK1
SCHEMBL13754143 0.80 NR1H4 (0.51) ACACBRAB9ATP53TSHRNR1H4
SCHEMBL13754142 0.78 ACACB (0.45) MEN1KMT2AALDH1A1LMNAACACB
SCHEMBL4445520 0.78 MEN1 (0.41) MEN1KMT2AALDH1A1LMNAACACB
SCHEMBL13754141 0.77 NR4A2 (0.44) MEN1KMT2ALMNAACACBNPC1
SCHEMBL13754169 0.77 NR1H4 (0.45) LMNAMAPTSMN1; SMN2NR1H4
SCHEMBL13754176 0.76 ESRRG (0.44) MEN1KMT2AALDH1A1LMNAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572938-B2 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2009-08-11 US disclosed
US-7572938-B2 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2009-08-11 US disclosed