Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754159 | 0.86 | ALOX15 (0.51) | ALOX15NFE2L2KDM4EALDH1A1MEN1 | |
| SCHEMBL4405863 | 0.84 | ALOX15 (0.43) | ALOX15NFE2L2KDM4EALDH1A1HPGD | |
| SCHEMBL13754147 | 0.82 | ALOX15 (0.48) | ALOX15NFE2L2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL7940744 | 0.82 | ALOX15 (0.45) | ALOX15NFE2L2KDM4EALDH1A1HPGD | |
| SCHEMBL23925273 | 0.79 | ALOX15 (0.41) | ALOX15NFE2L2KDM4EALDH1A1HPGD | |
| SCHEMBL22443740 | 0.79 | ALOX15 (0.41) | ALOX15NFE2L2KDM4EALDH1A1HPGD | |
| SCHEMBL21596602 | 0.79 | ALOX15 (0.41) | ALOX15NFE2L2KDM4EALDH1A1HPGD | |
| SCHEMBL21596570 | 0.77 | ALOX15 (0.39) | ALOX15NFE2L2KDM4EALDH1A1HPGD | |
| SCHEMBL13754156 | 0.77 | TP53 (0.47) | ALOX15GAATP53 | |
| SCHEMBL4450364 | 0.77 | TP53 (0.47) | ALOX15GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572938-B2 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2009-08-11 | — | — | US | disclosed |