Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405863 | 0.89 | ALOX15 (0.43) | ALOX15HPGDKDM4ESMN1; SMN2PTPN1 | |
| SCHEMBL21596570 | 0.89 | ALOX15 (0.39) | ALOX15HPGDKDM4ESMN1; SMN2HDAC1 | |
| SCHEMBL17861023 | 0.86 | ALOX15 (0.51) | ALOX15KDM4ESMN1; SMN2NFE2L2ALDH1A1 | |
| SCHEMBL17861077 | 0.86 | ALOX15 (0.51) | ALOX15KDM4ESMN1; SMN2NFE2L2ALDH1A1 | |
| SCHEMBL19680576 | 0.86 | ALOX15 (0.51) | ALOX15KDM4ESMN1; SMN2NFE2L2ALDH1A1 | |
| SCHEMBL7940736 | 0.82 | ALOX15 (0.48) | ALOX15HDAC1NFE2L2ALDH1A1MAPT | |
| SCHEMBL19680580 | 0.82 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1MAPTNPC1 | |
| SCHEMBL17861084 | 0.82 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1MAPTNPC1 | |
| SCHEMBL17861078 | 0.82 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1MAPTNPC1 | |
| SCHEMBL7948852 | 0.82 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258854-B1 | KETONE ETHERS FOR ODORS | GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) | 2001-07-10 | — | — | US | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |