Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 5/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.33 |
| ▸ | NCOR1 | O75376 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402036 | 1.00 | HRH3 (0.39) | HRH3MLNRHDAC3HDAC1HDAC2 | |
| SCHEMBL4399705 | 0.90 | HRH3 (0.34) | HRH3MLNR | |
| SCHEMBL4399717 | 0.86 | ITGB3 (0.41) | HRH3MLNRHDAC1HDAC6HDAC8 | |
| SCHEMBL15762025 | 0.86 | ITGB3 (0.41) | HRH3MLNRHDAC1HDAC6HDAC8 | |
| SCHEMBL16840265 | 0.86 | ITGB3 (0.41) | HRH3MLNRHDAC1HDAC6HDAC8 | |
| SCHEMBL12019149 | 0.86 | ITGB3 (0.41) | HRH3MLNRHDAC1HDAC6HDAC8 | |
| SCHEMBL15762029 | 0.80 | HRH3 (0.40) | HRH3MLNRHDAC3HDAC1HDAC2 | |
| SCHEMBL4402045 | 0.80 | HRH3 (0.40) | HRH3MLNRHDAC3HDAC1HDAC2 | |
| SCHEMBL13784332 | 0.80 | HRH3 (0.40) | HRH3MLNRHDAC3HDAC1HDAC2 | |
| SCHEMBL2672144 | 0.80 | HRH3 (0.40) | HRH3MLNRHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100431-A1 | CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | MARQUETTE UNIVERSITY (US) | 2009-08-13 | — | — | WO | disclosed |