Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354734 | 0.86 | CNR1 (0.53) | POLBLMNAKDM4EAPOBEC3AGFER | |
| SCHEMBL92190 | 0.86 | POLB (0.62) | POLBLMNAKDM4EAPOBEC3AGFER | |
| SCHEMBL13175172 | 0.86 | POLB (0.54) | POLBLMNAKDM4EAPOBEC3AGFER | |
| SCHEMBL8787958 | 0.83 | POLB (0.51) | POLBLMNAKDM4EAPOBEC3AGFER | |
| SCHEMBL6581850 | 0.82 | ALDH1A1 (0.52) | POLBLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4513447 | 0.81 | KDM4E (0.54) | POLBLMNAKDM4EAPOBEC3AGFER | |
| SCHEMBL8225325 | 0.81 | SMN1; SMN2 (0.47) | POLBLMNAKDM4EHDAC1SMN1; SMN2 | |
| SCHEMBL30667032 | 0.81 | ALDH1A1 (0.59) | POLBKDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL14405814 | 0.81 | ALDH1A1 (0.59) | POLBKDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL16139300 | 0.80 | TRPA1 (0.46) | LMNAKDM4ESMN1; SMN2TRPA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |