Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417811 | 0.77 | PKM (0.39) | MAPTPOLBTP53SMN1; SMN2HTT | |
| SCHEMBL18891692 | 0.74 | DYRK1A (0.42) | MAPTPOLBTP53SMN1; SMN2HTT | |
| SCHEMBL13990817 | 0.73 | ALOX12 (0.56) | MAPTSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL14754844 | 0.70 | NR1I3 (0.52) | MAPTPOLBTP53SMN1; SMN2NPC1 | |
| SCHEMBL17039300 | 0.68 | DYRK1A (0.51) | MAPTPOLBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL1692245 | 0.67 | NR1I3 (0.55) | MAPTPOLBTP53DYRK1ANR1I3 | |
| SCHEMBL6099806 | 0.66 | DYRK1A (0.57) | MAPTPOLBTP53SMN1; SMN2NPC1 | |
| SCHEMBL20878604 | 0.66 | DYRK1A (0.45) | MAPTPOLBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL6100431 | 0.66 | DYRK1A (0.49) | MAPTTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20078261 | 0.66 | IDO1 (0.57) | MAPTTP53HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |