Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128370 | 0.98 | ANPEP (0.34) | SPHK1SPHK2CYP2D6NOD1ANPEP | |
| SCHEMBL13191824 | 0.93 | ANPEP (0.35) | ANPEPENPEPOPRM1 | |
| SCHEMBL91243 | 0.85 | ANPEP (0.38) | ANPEPENPEP | |
| SCHEMBL12928341 | 0.82 | ANPEP (0.35) | ANPEPENPEP | |
| SCHEMBL29328248 | 0.81 | OPRM1 (0.39) | SPHK1SPHK2CYP2D6NOD1GMNN | |
| SCHEMBL26537541 | 0.80 | ANPEP (0.38) | SPHK1ANPEPFNTAFNTB | |
| SCHEMBL22986927 | 0.77 | SPHK2 (0.41) | SPHK1SPHK2FFAR4FFAR1 | |
| SCHEMBL804904 | 0.77 | ANPEP (0.40) | ANPEPENPEP | |
| SCHEMBL16215356 | 0.77 | ANPEP (0.36) | ANPEPENPEP | |
| Stearic Acid SCHEMBL10341020 | 0.76 | BHMT (0.62) | BHMTFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090202579-A1 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING MALARIA (2) | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL (AU) | 2009-08-13 | — | — | US | disclosed |