Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817099 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1CASP2NAAAMAPT | |
| SCHEMBL24412633 | 0.83 | CASP2 (0.65) | KDM4ECASP2NAAASMN1; SMN2TP53 | |
| SCHEMBL24412952 | 0.83 | CASP2 (0.65) | KDM4ECASP2NAAASMN1; SMN2TP53 | |
| SCHEMBL23442084 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH | |
| SCHEMBL23443054 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH | |
| SCHEMBL23442081 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH | |
| SCHEMBL23442902 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH | |
| SCHEMBL23442903 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH | |
| SCHEMBL23442089 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH | |
| SCHEMBL23442899 | 0.82 | CASP2 (0.59) | CASP2NAAAEPHX1NOD1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097332-A2 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |