Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | FPR3 | P25089 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21827446 | 0.92 | KDM4E (0.60) | KDM4ECASP2MAPTNAAAALDH1A1 | |
| SCHEMBL24412952 | 0.92 | CASP2 (0.65) | KDM4ECASP2NAAAFAAHGNAI3 | |
| SCHEMBL24412633 | 0.92 | CASP2 (0.65) | KDM4ECASP2NAAAFAAHGNAI3 | |
| SCHEMBL24001250 | 0.91 | KDM4E (0.59) | KDM4ECASP2NAAAALDH1A1FAAH | |
| SCHEMBL21998740 | 0.88 | KDM4E (0.62) | KDM4ECASP2MAPTALDH1A1FAAH | |
| SCHEMBL21998674 | 0.88 | KDM4E (0.62) | KDM4ECASP2MAPTALDH1A1FAAH | |
| SCHEMBL24412716 | 0.88 | CASP2 (0.59) | KDM4ECASP2NAAAALDH1A1FAAH | |
| SCHEMBL21998662 | 0.88 | KDM4E (0.62) | KDM4ECASP2MAPTALDH1A1FAAH | |
| SCHEMBL9633481 | 0.88 | KDM4E (0.62) | KDM4ECASP2MAPTALDH1A1FAAH | |
| SCHEMBL8587735 | 0.88 | KDM4E (0.62) | KDM4ECASP2MAPTALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | KDM4E 812/4885CASP2 248/4885MAPT 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.