SCHEMBL13756261

SCHEMBL13756261

C[Si](C)(CCCC(CC(=O)O)C(=O)O)O[Si](C)(C)CCCC(CC(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 10/20 0.47
CA2 P00918 1/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
CPA1 P15085 2/20 0.33
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CPB1 P15086 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786883 0.94 CA2 (0.44) FOLH1CA2MAPK1CHRM1AKR1A1
SCHEMBL786932 0.93 FOLH1 (0.44) FOLH1CA2MAPK1MEN1GAA
SCHEMBL13151579 0.92 FOLH1 (0.43) FOLH1CA2MAPK1MEN1GAA
SCHEMBL13318396 0.88 FOLH1 (0.38) FOLH1CA2MAPK1MEN1GAA
SCHEMBL20492090 0.88 FOLH1 (0.46) FOLH1CA2MAPK1MEN1GAA
SCHEMBL13042895 0.84 FOLH1 (0.37) FOLH1MEN1GAAKMT2A
SCHEMBL787058 0.83 FOLH1 (0.52) FOLH1CA2MAPK1MEN1GAA
SCHEMBL786839 0.83 FOLH1 (0.44) FOLH1CA2MAPK1MEN1GAA
SCHEMBL13042907 0.83 CPA1 (0.41) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL20127162 0.82 FOLH1 (0.33) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160194456-A1 CROSS-LINKED COMPOSITION AND METHOD OF FORMING THE SAME DOW CORNING CORPORATION (US) 2016-07-07 US disclosed
US-7572842-B2 Automixable putty impression material 3M ESPE AG 2009-08-11 US disclosed