Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644625 | 0.85 | KDM1A (0.40) | NOS2KDM1ARAPGEF4MAOBMAPK1 | |
| SCHEMBL1842397 | 0.81 | RAPGEF4 (0.46) | NOS2KDM1ARAPGEF4MAPK1BRD4 | |
| SCHEMBL13419405 | 0.78 | BRD4 (0.43) | NOS2KDM1AMAOBMAPK1BRD4 | |
| SCHEMBL12074539 | 0.77 | POLB (0.44) | RAPGEF4BRD4ATAD2ALDH1A1EHMT2 | |
| SCHEMBL14413848 | 0.74 | MAPT (0.40) | NOS2MAPK1BRD4ATAD2CYP1A2 | |
| SCHEMBL12989403 | 0.73 | KDM4E (0.54) | ALDH1A1EHMT2MEN1KMT2A | |
| SCHEMBL17918746 | 0.72 | HTR2C (0.46) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3973338 | 0.71 | BRD4 (0.44) | RAPGEF4BRD4ATAD2EHMT2HRH3 | |
| SCHEMBL4753171 | 0.71 | BRD4 (0.40) | NOS2KDM1AMAOBMAPK1BRD4 | |
| SCHEMBL11457761 | 0.70 | HTR2C (0.49) | KDM1ABRD4ATAD2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569561-B2 | 2,4-diaminopyrimidines useful for treating cell proliferation diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-20070207999-A1 | New Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207999-A1 | New Compounds | CCNA1, MKI67, CCNT1 | NOS2 3143/4885KDM1A 1480/4885RAPGEF4 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.