Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421297 | 0.78 | BRD4 (0.36) | BRD4ATAD2KDM1AMAOBMAPK1 | |
| SCHEMBL4965097 | 0.75 | BRD4 (0.41) | BRD4ATAD2KDM1AMAOBMAPK1 | |
| SCHEMBL13419405 | 0.74 | BRD4 (0.43) | BRD4ATAD2KDM1AMAOBMAPK1 | |
| SCHEMBL13756997 | 0.71 | NOS2 (0.41) | BRD4ATAD2KDM1AMAOBMAPK1 | |
| SCHEMBL14937570 | 0.71 | HTR2C (0.46) | — | |
| SCHEMBL20817932 | 0.71 | BRD4 (0.46) | BRD4ATAD2MAPK1CYP1A2CYP3A4 | |
| SCHEMBL12277378 | 0.70 | BRD4 (0.48) | BRD4ATAD2KDM1AMAPK1CYP1A2 | |
| SCHEMBL10820261 | 0.70 | NPC1 (0.43) | BRD4ATAD2KDM1AMAOBMAPK1 | |
| SCHEMBL4964715 | 0.70 | MAPT (0.48) | BRD4ATAD2MAPK1CYP1A2CYP3A4 | |
| SCHEMBL377687 | 0.69 | KDM4E (0.53) | BRD4ATAD2KDM1AMAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |