Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757219 | 0.81 | MAPK1 (0.34) | MAPK1GAAMAPTHSD17B10GAK | |
| SCHEMBL16284912 | 0.73 | LIMK1 (0.33) | MAPK1GAAMAPTHSD17B10GAK | |
| SCHEMBL12194735 | 0.73 | LIMK1 (0.33) | MAPK1GAAMAPTHSD17B10GAK | |
| SCHEMBL10314556 | 0.73 | ELANE (0.35) | MAPK1HSD17B10ELANE | |
| SCHEMBL16284922 | 0.70 | NOS1 (0.33) | NOS1 | |
| SCHEMBL16284930 | 0.69 | LIMK1 (0.31) | MAPK1GAAMAPTHSD17B10LIMK1 | |
| SCHEMBL15142408 | 0.69 | LIMK1 (0.31) | MAPK1GAAMAPTHSD17B10LIMK1 | |
| SCHEMBL2388405 | 0.69 | LIMK1 (0.31) | MAPK1GAAMAPTHSD17B10LIMK1 | |
| SCHEMBL15142122 | 0.68 | LIMK1 (0.33) | MAPK1GAAMAPTHSD17B10GAK | |
| SCHEMBL12194737 | 0.67 | LIMK1 (0.30) | LIMK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791262-B2 | Asymmetric friedel-crafts alkylations catalyzed by bifunctional cinchona alkaloids | BRANDEIS UNIVERSITY (US) | 2014-07-29 | — | — | US | disclosed |
| US-20090203913-A1 | Asymmetric Friedel-Crafts Alkylations Catalyzed By Bifunctional Cinchona Alkaloids | BRANDEIS UNIVERSITY | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203913-A1 | Asymmetric Friedel-Crafts Alkylations Catalyzed By Bifunctional Cinchona Alkaloids | COASY, AANAT, PCNA | MAPK1 4725/4885GAA 639/4885MAPT 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.