Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | STAT5A | P42229 | 2/20 | 0.41 |
| ▸ | STAT5B | P51692 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062828 | 0.89 | PTGER2 (0.52) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL13063095 | 0.89 | PTGER2 (0.58) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL13063094 | 0.88 | PTGER2 (0.50) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL13757306 | 0.87 | PTGER2 (0.53) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL3062083 | 0.86 | PTGER2 (0.67) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL29781355 | 0.86 | PTGER2 (0.67) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL29372302 | 0.86 | PTGER2 (0.67) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL3662869 | 0.85 | PTGER2 (0.52) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL3659169 | 0.85 | PTGER2 (0.55) | PTGER2SMN1; SMN2AHRMAPTLMNA | |
| SCHEMBL3660760 | 0.84 | ALDH1A1 (0.55) | PTGER2SMN1; SMN2AHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098458-A2 | BIARYL AMIDES | ASTERAND UK LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |