Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757306 | 0.90 | PTGER2 (0.53) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL13757307 | 0.89 | PTGER2 (0.51) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL13063095 | 0.89 | PTGER2 (0.58) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL13063094 | 0.89 | PTGER2 (0.50) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL13017411 | 0.88 | PTGER2 (0.52) | PTGER2SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL3660760 | 0.87 | ALDH1A1 (0.55) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL29781355 | 0.87 | PTGER2 (0.67) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL3062083 | 0.87 | PTGER2 (0.67) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL29372302 | 0.87 | PTGER2 (0.67) | PTGER2SMN1; SMN2AHRRAB9ANPC1 | |
| SCHEMBL3050603 | 0.86 | PTGER2 (0.52) | PTGER2SMN1; SMN2AHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331410-A1 | Biaryl Amides | ASTERAND UK LIMITED (GB) | 2010-12-30 | — | — | US | disclosed |
| WO-2009098458-A2 | BIARYL AMIDES | ASTERAND UK LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331410-A1 | Biaryl Amides | AGTR2, CYP11B2, ALDH1A2 | PTGER2 242/4885SMN1; SMN2 4848/4885AHR 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.