Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837473 | 0.86 | TSHR (0.60) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL3515887 | 0.86 | TSHR (0.60) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL277304 | 0.84 | TSHR (0.53) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL2568123 | 0.83 | CA12 (0.56) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL12447815 | 0.83 | TSHR (0.52) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL3290788 | 0.81 | TSHR (0.50) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL14398405 | 0.81 | TSHR (0.50) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL1841640 | 0.81 | ALDH1A1 (0.68) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL1213901 | 0.81 | CASP1 (0.52) | TSHRNUDT1ALDH1A1MEN1KMT2A | |
| SCHEMBL29790003 | 0.81 | ALDH1A1 (0.68) | TSHRNUDT1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097014-A2 | THERAPEUTIC KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-08-06 | — | — | WO | disclosed |