Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144067 | 0.83 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL10489040 | 0.82 | CYP2A6 (0.69) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL27821745 | 0.82 | CYP2A6 (0.69) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL29467928 | 0.78 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL19180195 | 0.78 | CYP2A6 (0.70) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL38654556 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL14318134 | 0.78 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL79559 | 0.78 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL315329 | 0.78 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL30782674 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137771-A1 | METHOD FOR SYNTHESIZING α-ALKYL SUBSTITUTED INDOLE-3-CARBOXALDEHYDE COMPOUND | 苏州大学 | 2023-07-27 | — | — | WO | claimed |
| CN-114478351-B | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2023-04-28 | — | — | CN | claimed |
| CN-114478351-A | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2022-05-13 | — | — | CN | claimed |
| CN-110330535-B | N-heterocyclic carbene-based mixed nickel (II) complex and application thereof | 苏州大学 | 2022-04-15 | — | — | CN | claimed |
| CN-110330535-A | N-heterocyclic carbine base mixed matching nickel (II) complex and its application | 苏州大学 | 2019-10-15 | — | — | CN | claimed |
| WO-2023137771-A1 | METHOD FOR SYNTHESIZING α-ALKYL SUBSTITUTED INDOLE-3-CARBOXALDEHYDE COMPOUND | 苏州大学 | 2023-07-27 | — | — | WO | disclosed |
| WO-2023137771-A1 | METHOD FOR SYNTHESIZING α-ALKYL SUBSTITUTED INDOLE-3-CARBOXALDEHYDE COMPOUND | 苏州大学 | 2023-07-27 | — | — | WO | disclosed |
| CN-114478351-B | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-114478351-B | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-114478351-A | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478351-A | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-110330535-B | N-heterocyclic carbene-based mixed nickel (II) complex and application thereof | 苏州大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-110330535-B | N-heterocyclic carbene-based mixed nickel (II) complex and application thereof | 苏州大学 | 2022-04-15 | — | — | CN | disclosed |
| WO-2021209765-A2 | METHODS AND PRODUCTS | THE UNIVERSITY OF BIRMINGHAM (GB) | 2021-10-21 | — | — | WO | disclosed |
| CN-110330535-A | N-heterocyclic carbine base mixed matching nickel (II) complex and its application | 苏州大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-110330535-A | N-heterocyclic carbine base mixed matching nickel (II) complex and its application | 苏州大学 | 2019-10-15 | — | — | CN | disclosed |
| US-20130289022-A1 | TETRAMERIC ALPHA-SYNUCLEIN AND USE THEREOF | BRANDEIS UNIVERSITY (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2009100406-A2 | TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS | SYNTA PHARMACEUTICALS CORP. (US) | 2009-08-13 | — | — | WO | disclosed |
| WO-2007100759-A2 | METHOD FOR TREATING COMMON VARIABLE IMMUNODEFICIENCY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-09-07 | — | — | WO | disclosed |