Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821745 | 0.86 | CYP2A6 (0.69) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| SCHEMBL7275100 | 0.83 | CYP2A6 (0.60) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| SCHEMBL13083133 | 0.83 | CYP2A6 (0.60) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| SCHEMBL10489040 | 0.82 | CYP2A6 (0.69) | CYP2A6IMPDH2HPGDHTTATM | |
| SCHEMBL3621033 | 0.79 | CYP2A6 (0.60) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| SCHEMBL7370729 | 0.79 | SIRT2 (0.46) | CYP2A6IMPDH2HPGDHTTATM | |
| SCHEMBL14161292 | 0.79 | CYP2A6 (0.55) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| SCHEMBL19889385 | 0.79 | CYP2A6 (0.55) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| 3-Formylindole SCHEMBL19180195 | 0.78 | CYP2A6 (0.70) | CYP2A6IMPDH2HPGDHTTPTGS2 | |
| 3-Formylindole SCHEMBL56373 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624955-B | Separation method of 3-indoloethyl (3 '-methyl-2' -ketone) valeramide | 西北农林科技大学 | 2024-07-09 | — | — | CN | claimed |
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| CN-113292430-B | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | claimed |
| EP-3523316-B1 | MELANOCORTIN-1-RECEPTOR AGONISTS | DSM IP ASSETS BV (NL) | 2021-11-03 | — | — | EP | claimed |
| US-20210277058-A1 | MELANOCORTIN-1-RECEPTOR AGONISTS | DSM IP ASSETS B.V. (NL) | 2021-09-09 | — | — | US | claimed |
| CN-113292430-A | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2021-08-24 | — | — | CN | claimed |
| CN-112624955-A | Separation method of 3-indolylethyl (3 '-methyl-2' -ketone) valeramide | 西北农林科技大学 | 2021-04-09 | — | — | CN | claimed |
| EP-3692978-A1 | NOVEL METHOD | DSM IP Assets B.V. (NL) | 2020-08-12 | — | — | EP | claimed |
| CN-111344013-A | Use of NOX inhibitors for the treatment of cancer | 吉恩基奥泰克斯瑞士股份有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-106397254-A | Chiral 8-hydroxyhomodrimane sesquiterpene amide compound and application of same as agricultural bactericide | 南京农业大学 | 2017-02-15 | — | — | CN | claimed |
| EP-0357316-A1 | Antidepressant N-substituted nicotinamide compounds | PFIZER INC. (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0181152-B1 | PIPERAZINE COMPOUND AS PAF-ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | claimed |
| US-4861891-A | Antidepressant N-substituted nicotinamide compounds | PFIZER INC. (US) | 1989-08-29 | — | — | US | claimed |
| EP-0251194-A1 | Use of carbocyclic and heterocyclic condensed dihydropyridines for the preparation of cardioprotective remedies and heterocyclic and carbocyclic condensed dihydropyridines and methods and intermediates for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1988-01-07 | — | — | EP | claimed |
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
| EP-0181152-A1 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | claimed |
| US-4563464-A | 2-Azabicyclo(2.2.2)octane derivatives and their use as immunosuppressive agents | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-01-07 | — | — | US | claimed |
| US-4528293-A | Heteroaromatic derivatives of iminomethyl piperidines and use to inhibit gastric acid secretion | MCNEILAB, INC. (US) | 1985-07-09 | — | — | US | claimed |
| US-4199512-A | Compounds for alleviating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1980-04-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277058-A1 | MELANOCORTIN-1-RECEPTOR AGONISTS | MC1R, MC3R, MC5R | CYP2A6 4564/4885IMPDH2 4610/4885HPGD 1765/4885 |
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | ABCC1, ABCC2, ERG28 | CYP2A6 1565/4885IMPDH2 2781/4885HPGD 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.