Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13759052 | 0.83 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL10489040 | 0.82 | CYP2A6 (0.69) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL27821745 | 0.82 | CYP2A6 (0.69) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL38654556 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL30782674 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL14318134 | 0.78 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL30786737 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP | |
| SCHEMBL79559 | 0.78 | CYP2A6 (0.64) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL19180195 | 0.78 | CYP2A6 (0.70) | CYP2A6IMPDH2HPGDHTTAPP | |
| 3-Formylindole SCHEMBL56373 | 0.78 | CYP2A6 (1.00) | CYP2A6IMPDH2HPGDHTTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110444674-A | Organic light emitting apparatus and its manufacturing method | SPRING FOUNDATION OF NATIONAL CHIAO TUNG UNIV | 2019-11-12 | — | — | CN | claimed |
| US-20110301217-A1 | Selective Glycosidase Inhibitors and Uses Thereof | SIMON FRASER UNIVERSITY (CA) | 2011-12-08 | — | — | US | claimed |
| CN-102200514-A | Method for analyzing sulphydryl amino acid by colorimetric detection | LANZHOU CHEM PHYS INST | 2011-09-28 | — | — | CN | claimed |
| EP-2344452-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | Simon Fraser University (CA) | 2011-07-20 | — | — | EP | claimed |
| WO-2010037207-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2010-04-08 | — | — | WO | claimed |
| CN-115745898-A | Aromatic acrylamide-triazole compound, and preparation method and application thereof | 许昌学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-108309977-B | Application of indole ethylene substituted quinoline derivative in preparation of drug-resistant bacteria resistant drugs | 广东工业大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-110444674-A | Organic light emitting apparatus and its manufacturing method | SPRING FOUNDATION OF NATIONAL CHIAO TUNG UNIV | 2019-11-12 | — | — | CN | disclosed |
| CN-107311977-A | A kind of indoles ethylene compounds and its preparation method and application | 广东工业大学 | 2017-11-03 | — | — | CN | disclosed |
| US-20110301217-A1 | Selective Glycosidase Inhibitors and Uses Thereof | SIMON FRASER UNIVERSITY (CA) | 2011-12-08 | — | — | US | disclosed |
| CN-102200514-A | Method for analyzing sulphydryl amino acid by colorimetric detection | LANZHOU CHEM PHYS INST | 2011-09-28 | — | — | CN | disclosed |
| EP-2344452-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | Simon Fraser University (CA) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010037207-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2010-04-08 | — | — | WO | disclosed |
| US-20080221157-A1 | Amide Derivatives as Inhibitors of Histone Deacetylase | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGE (IT) | 2008-09-11 | — | — | US | disclosed |
| CN-101107220-A | Amide derivatives as inhibitors of histone deacetylase | ANGELETTI P INST RICHERCHE BIO (IT) | 2008-01-16 | — | — | CN | disclosed |
| EP-1768955-A1 | AMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006005941-A1 | AMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI S.P.A. (IT) | 2006-01-19 | — | — | WO | disclosed |
| WO-2001019791-A2 | 3-VINYLPYRROLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | MORPHOCHEM AG (DE) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301217-A1 | Selective Glycosidase Inhibitors and Uses Thereof | ENGASE, OGA, GPI | CYP2A6 3030/4885IMPDH2 198/4885HPGD 1949/4885 |
| US-20080221157-A1 | Amide Derivatives as Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC4 | CYP2A6 1949/4885IMPDH2 1831/4885HPGD 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.