SCHEMBL13760106

SCHEMBL13760106

CCCc1cc2ccc3cc(C)c(F)c(F)c3c2c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26802590 0.86 CTSL (0.31) CTSLCTSSCTSK
SCHEMBL13760105 0.86 ATM (0.37) CTSLCTSSCTSK
SCHEMBL19160913 0.85 HSD17B10 (0.33) CTSLCTSSCTSK
SCHEMBL13760107 0.84 TYR (0.41) CTSLCTSSCTSK
SCHEMBL17719291 0.83 CTSL (0.34) CTSLCTSSCTSK
SCHEMBL18220538 0.82 CTSL (0.38) CTSLCTSSCTSK
SCHEMBL170558 0.81 CYP1A2 (0.33)
SCHEMBL4813944 0.78 HMGCR (0.42) CTSLCTSSCTSK
SCHEMBL21115645 0.77 HDAC3 (0.32)
SCHEMBL19161174 0.76 HDAC3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7560147-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2009-07-14 US disclosed
US-7560147-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2009-07-14 US disclosed
US-20080193681-A1 Liquid-Crystal Medium MERCK PATENT GMBH (DE) 2008-08-14 US disclosed
US-20080193681-A1 Liquid-Crystal Medium MERCK PATENT GMBH (DE) 2008-08-14 US disclosed