Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13760105 | 0.87 | ATM (0.37) | MAPTCTSLCTSSCTSKATM | |
| SCHEMBL13760106 | 0.84 | CTSL (0.31) | CTSLCTSSCTSK | |
| SCHEMBL18220538 | 0.84 | CTSL (0.38) | TYRMEN1HTTKMT2ATP53 | |
| SCHEMBL17719291 | 0.81 | CTSL (0.34) | CTSLCTSSCTSK | |
| SCHEMBL26802590 | 0.81 | CTSL (0.31) | CTSLCTSSCTSK | |
| SCHEMBL19160913 | 0.79 | HSD17B10 (0.33) | TSHRCTSLCTSSCTSKKDM4E | |
| SCHEMBL4813944 | 0.79 | HMGCR (0.42) | CYP3A4ALOX5CTSLCTSSCTSK | |
| SCHEMBL19160422 | 0.79 | MEN1 (0.37) | TYRTLR8MEN1HTTKMT2A | |
| SCHEMBL19160424 | 0.78 | TYR (0.50) | TYRTLR8MEN1HTTKMT2A | |
| SCHEMBL20828855 | 0.77 | ALDH1A1 (0.40) | TYRMEN1HTTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560147-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| US-7560147-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| US-20080193681-A1 | Liquid-Crystal Medium | MERCK PATENT GMBH (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080193681-A1 | Liquid-Crystal Medium | MERCK PATENT GMBH (DE) | 2008-08-14 | — | — | US | disclosed |