SCHEMBL13760889

SCHEMBL13760889

CC(C)(C)C1=CC(=CN=Nc2ccc([N+](=O)[O-])cc2)C=C(C(C)(C)C)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.38
▸ KMT2A Q03164 7/20 0.38
▸ MAPT P10636 6/20 0.38
▸ RAB9A P51151 5/20 0.38
▸ NPC1 O15118 4/20 0.38
▸ MAPK1 P28482 3/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ TNNI3 P19429 1/20 0.38
▸ TNNT2 P45379 1/20 0.38
▸ TNNC1 P63316 1/20 0.38
▸ KEAP1 Q14145 1/20 0.38
▸ NFE2L2 Q16236 1/20 0.38
▸ NOS1 P29475 2/20 0.38
▸ CA12 O43570 3/20 0.37
▸ CA1 P00915 3/20 0.37
▸ CA2 P00918 3/20 0.37
▸ CA9 Q16790 3/20 0.37
▸ PTGS2 P35354 1/20 0.37
▸ ALDH1A1 P00352 4/20 0.37
▸ CASP3 P42574 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22238634 1.00 MEN1 (0.38) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL18877788 0.92 MEN1 (0.35) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL13580359 0.87 PTGS2 (0.38) MEN1KMT2AMAPTSMN1; SMN2CA12
SCHEMBL14280241 0.86 KMT2A (0.36) MEN1KMT2AMAPTNPC1MAPK1
SCHEMBL14280239 0.85 KMT2A (0.44) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL13580310 0.84 ATM (0.38) KMT2AMAPTNPC1SMN1; SMN2ALDH1A1
SCHEMBL13580331 0.83 KMT2A (0.34) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL13749169 0.83 ATM (0.37) KMT2AMAPTNPC1MAPK1SMN1; SMN2
SCHEMBL14280269 0.83 NPC1 (0.37) KMT2AMAPTRAB9ANPC1MAPK1
SCHEMBL13580425 0.82 PTPRC (0.40) MEN1KMT2AMAPTNPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
EP-2088471-A1 Electrophographic Photoreceptor and Electrophotographic Imaging Apparatus Using the Same Samsung Electronics Co., Ltd. (KR) 2009-08-12 — — EP disclosed
US-7396624-B2 Electrophotographic photoreceptor containing naphthalenetetracarboxylic acid diimide derivatives and electrophotographic imaging apparatus employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-07-08 — — US disclosed
US-7396624-B2 Electrophotographic photoreceptor containing naphthalenetetracarboxylic acid diimide derivatives and electrophotographic imaging apparatus employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-07-08 — — US disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 — — US disclosed
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