Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280241 | 0.87 | KMT2A (0.36) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL22238634 | 0.85 | MEN1 (0.38) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL13760889 | 0.85 | MEN1 (0.38) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL13580408 | 0.83 | NPC1 (0.37) | KMT2ANPC1 | |
| SCHEMBL14280247 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL13580331 | 0.81 | KMT2A (0.34) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL18877729 | 0.81 | KMT2A (0.37) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL18877737 | 0.81 | KMT2A (0.38) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL18877739 | 0.81 | KMT2A (0.36) | KMT2AMEN1NPC1TDP1CA1 | |
| SCHEMBL13580359 | 0.81 | PTGS2 (0.38) | KMT2AMEN1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |