Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710167 | 0.84 | APEX1 (0.41) | APEX1KMT2AALDH1A1TP53HRH3 | |
| SCHEMBL13710177 | 0.83 | APEX1 (0.40) | APEX1KMT2AALDH1A1TP53HRH3 | |
| SCHEMBL13761049 | 0.82 | APEX1 (0.41) | APEX1KMT2AALDH1A1TP53HRH3 | |
| SCHEMBL16153985 | 0.76 | NR1H3 (0.44) | KMT2AALDH1A1TP53RAB9APOLB | |
| SCHEMBL13761079 | 0.74 | APEX1 (0.41) | APEX1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL2349906 | 0.74 | ACACB (0.55) | CDC7DBF4 | |
| SCHEMBL13710221 | 0.73 | APEX1 (0.44) | APEX1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL13712403 | 0.71 | APEX1 (0.37) | APEX1KMT2ATP53HRH3RAB9A | |
| SCHEMBL13710236 | 0.70 | WRN (0.47) | APEX1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL13761088 | 0.69 | APEX1 (0.45) | APEX1KMT2AALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |