Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARG | P13631 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761065 | 0.90 | RARA (0.48) | ALDH1A1KMT2ARARARARBRARG | |
| SCHEMBL13761059 | 0.89 | RARA (0.40) | APEX1ALDH1A1RARARARBRARG | |
| SCHEMBL13761087 | 0.81 | RARA (0.44) | APEX1LMNAALDH1A1KMT2ARARA | |
| SCHEMBL13761095 | 0.77 | KMT2A (0.42) | APEX1LMNAALDH1A1KMT2ARARA | |
| SCHEMBL13710221 | 0.77 | APEX1 (0.44) | APEX1LMNAALDH1A1KMT2ARARA | |
| SCHEMBL13761049 | 0.75 | APEX1 (0.41) | APEX1LMNAALDH1A1KMT2ARARA | |
| SCHEMBL14066574 | 0.75 | ACACB (0.38) | ALDH1A1KMT2AKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL13710236 | 0.74 | WRN (0.47) | APEX1LMNAALDH1A1KMT2ARARA | |
| SCHEMBL14066722 | 0.72 | ACACB (0.36) | GAA | |
| SCHEMBL13761079 | 0.72 | APEX1 (0.41) | APEX1LMNAALDH1A1KMT2ARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |