Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710187 | 0.88 | RARA (0.42) | APEX1ALDH1A1RARARARBRARG | |
| SCHEMBL13710195 | 0.88 | RARA (0.49) | ALDH1A1KMT2ARARARARBRARG | |
| SCHEMBL13710236 | 0.85 | WRN (0.47) | APEX1ALDH1A1KMT2ARARARARB | |
| SCHEMBL13710167 | 0.84 | APEX1 (0.41) | APEX1ALDH1A1KMT2ARARARARB | |
| SCHEMBL13710228 | 0.80 | RARA (0.46) | APEX1KMT2ARARARARBRARG | |
| SCHEMBL13710177 | 0.79 | APEX1 (0.40) | APEX1ALDH1A1KMT2ARARARARB | |
| SCHEMBL13761079 | 0.78 | APEX1 (0.41) | APEX1ALDH1A1KMT2ARARARARB | |
| SCHEMBL13761088 | 0.77 | APEX1 (0.45) | APEX1ALDH1A1KMT2ARARARARB | |
| SCHEMBL13710244 | 0.75 | LMNA (0.46) | APEX1KMT2ARARARARBRARG | |
| SCHEMBL13710191 | 0.75 | PIK3CD (0.41) | ALDH1A1KMT2ARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595404-B2 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents | BAYER CROPSCIENCE AG (DE) | 2009-09-29 | — | — | US | disclosed |
| US-7595404-B2 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents | BAYER CROPSCIENCE AG (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | DDT, CYP4B1, CYP1B1 | APEX1 1912/4885ALDH1A1 620/4885KMT2A 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.