Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710178 | 0.86 | HRH3 (0.41) | HRH3TRPM8KMT2AADORA3CA1 | |
| SCHEMBL13761050 | 0.82 | KMT2A (0.42) | HRH3TRPM8KMT2AADORA3CA1 | |
| SCHEMBL13761081 | 0.77 | MAPT (0.38) | HRH3TRPM8KMT2ANPC1POLB | |
| SCHEMBL13761086 | 0.77 | MAPT (0.44) | HRH3TRPM8KMT2APOLBRARA | |
| SCHEMBL13761076 | 0.77 | RARA (0.42) | HRH3TRPM8KMT2ARARARARB | |
| SCHEMBL13761083 | 0.73 | HRH3 (0.43) | HRH3NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL13761054 | 0.72 | RARA (0.47) | HRH3TRPM8RARARARBRARG | |
| SCHEMBL14064280 | 0.72 | KMT2A (0.42) | HRH3TRPM8KMT2AADORA3NPC1 | |
| SCHEMBL13765964 | 0.71 | RARA (0.43) | HRH3TRPM8RARARARBRARG | |
| SCHEMBL13710172 | 0.71 | KMT2A (0.44) | HRH3TRPM8KMT2AADORA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |