Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761051 | 0.86 | HRH3 (0.40) | HRH3KMT2ATRPM8ADORA3CA1 | |
| SCHEMBL13710172 | 0.82 | KMT2A (0.44) | HRH3KMT2ATRPM8ADORA3NPC1 | |
| SCHEMBL14506986 | 0.79 | RARA (0.46) | HRH3KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13710244 | 0.76 | LMNA (0.46) | HRH3KMT2ATRPM8NPC1POLB | |
| SCHEMBL13710203 | 0.76 | RARA (0.43) | HRH3KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14064280 | 0.73 | KMT2A (0.42) | HRH3KMT2ATRPM8ADORA3NPC1 | |
| SCHEMBL10947384 | 0.72 | ELANE (0.38) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13710241 | 0.72 | KMT2A (0.42) | HRH3KMT2ATRPM8POLBKDM4E | |
| SCHEMBL10946106 | 0.72 | PGR (0.42) | KMT2ACA1CA2HPGD | |
| SCHEMBL13710181 | 0.71 | RARA (0.46) | HRH3TRPM8ALDH1A1RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595404-B2 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents | BAYER CROPSCIENCE AG (DE) | 2009-09-29 | — | — | US | disclosed |
| US-7595404-B2 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents | BAYER CROPSCIENCE AG (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135630-A1 | Thiazolyl-substsituted carbocylic 1,3-diones as pesticidal agents | DDT, CYP4B1, CYP1B1 | HRH3 2958/4885KMT2A 2192/4885TRPM8 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.