Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | CFD | P00746 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12140989 | 0.76 | OPRM1 (0.43) | OPRD1MAP4K1HTR1ASLC6A4 | |
| SCHEMBL1363925 | 0.76 | NMT1 (0.51) | MAP4K1NMT1PRMT6HTR1ASLC6A4 | |
| SCHEMBL3434754 | 0.76 | NMT1 (0.51) | MAP4K1NMT1PRMT6HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL1364491 | 0.75 | OPRM1 (0.42) | OPRD1MAP4K1SLC6A4 | |
| SCHEMBL12062836 | 0.72 | BCHE (0.41) | PRMT6CFDBCHEACHE | |
| SCHEMBL13761198 | 0.67 | GBA1 (0.57) | EEDNMT1SLC6A4BCHEACHE | |
| SCHEMBL1364179 | 0.67 | FAAH (0.47) | — | |
| SCHEMBL13187336 | 0.67 | CHRM3 (0.42) | DRD2HTR1ASLC6A4CHRNB4CHRNA3 | |
| SCHEMBL12954023 | 0.67 | CHRM3 (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL12954019 | 0.66 | CHRM2 (0.33) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100168-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |