Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909057 | 0.85 | CA12 (0.58) | CA12CA9KMT2ALMNAMEN1 | |
| SCHEMBL19941397 | 0.85 | KDM4E (0.57) | KMT2ALMNASCN1ASCN2ASCN3A | |
| SCHEMBL13761328 | 0.79 | SMN1; SMN2 (0.50) | KMT2AMEN1ALDH1A1ACACBNPC1 | |
| SCHEMBL14103063 | 0.79 | SCN1A (0.68) | CA12CA9KMT2ALMNAMEN1 | |
| SCHEMBL29351154 | 0.79 | SCN1A (0.71) | CA12CA9KMT2ALMNASCN1A | |
| SCHEMBL8158111 | 0.78 | NR1H4 (0.54) | CA12CA9KMT2ALMNAMEN1 | |
| SCHEMBL12347956 | 0.78 | EPHX2 (0.54) | CA12CA9KMT2ALMNAMEN1 | |
| SCHEMBL17407652 | 0.78 | CA12 (0.51) | CA12CA9KMT2ALMNAMEN1 | |
| SCHEMBL13607305 | 0.78 | HDAC8 (0.59) | KMT2AHPGDHDAC6ALDH1A1PLK1 | |
| SCHEMBL13702393 | 0.78 | PLK1 (0.66) | CA12CA9KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |