Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909057 | 0.91 | CA12 (0.58) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL4349764 | 0.89 | THRB (0.55) | MAPTLMNAKMT2AMEN1THRB | |
| SCHEMBL10789232 | 0.83 | EPHX2 (0.60) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL92285 | 0.83 | GFER (0.59) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL9625469 | 0.83 | MPO (0.59) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL13702393 | 0.83 | PLK1 (0.66) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL10604141 | 0.83 | LMNA (0.63) | MAPTLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL12347956 | 0.83 | EPHX2 (0.54) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL8158111 | 0.83 | NR1H4 (0.54) | CA12CA9MAPTHPGDLMNA | |
| SCHEMBL4151490 | 0.83 | LMNA (0.63) | CA12CA9MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688818-B2 | Poly(ether sulfone)s and poly(ether amide sulfone)s and methods of their preparation | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160251480-A1 | POLY(ETHER SULFONE)S AND POLY(ETHER AMIDE SULFONE)S AND METHODS OF THEIR PREPARATION | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-09-01 | — | — | US | disclosed |
| US-9371431-B2 | Poly(ether sulfone)s and poly(ether amide sulfone)s and methods of their preparation | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160002431-A1 | POLY(ETHER SULFONE)S AND POLY(ETHER AMIDE SULFONE)S AND METHODS OF THEIR PREPARATION | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-01-07 | — | — | US | disclosed |