Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | CA2 | P00918 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 6/20 | 0.76 |
| ▸ | CA1 | P00915 | 5/20 | 0.76 |
| ▸ | CA9 | Q16790 | 5/20 | 0.76 |
| ▸ | CA12 | O43570 | 3/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.68 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564517 | 0.89 | RAB9A (0.67) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL13764395 | 0.87 | CA2 (0.78) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL13764561 | 0.86 | CA2 (1.00) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL1520437 | 0.82 | RAB9A (1.00) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL14612489 | 0.80 | RAB9A (0.77) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL11887688 | 0.79 | CA2 (1.00) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL22289694 | 0.79 | RAB9A (0.79) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL4625331 | 0.77 | GAA (0.51) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL8615629 | 0.77 | RAB9A (0.81) | ALDH1A1CA2LMNACA1CA9 | |
| SCHEMBL13785020 | 0.76 | CA2 (0.87) | ALDH1A1CA2LMNACA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877970-B2 | Inhibitors of carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-20090175794-A1 | INHIBITORS OF CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175794-A1 | INHIBITORS OF CARBONIC ANHYDRASE IX | CA9, CA12, CA1 | ALDH1A1 2166/4885CA2 7/4885LMNA 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.