SCHEMBL1376445

SCHEMBL1376445

CN(C)c1ccccc1-c1ccc(C(c2ccc(-c3ccccc3N(C)C)cc2)c2ccccc2COCc2ccccc2C(c2ccc(-c3ccccc3N(C)C)cc2)c2ccc(-c3ccccc3N(C)C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.33
NSD2 O96028 1/20 0.32
ALDH1A1 P00352 1/20 0.32
EGFR P00533 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TACR1 P25103 1/20 0.32
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407505 0.80 MAPT (0.37) GRM5NSD2ALDH1A1EGFRLMNA
SCHEMBL8650691 0.80 CNR2 (0.40) GRM5NSD2ALDH1A1EGFRLMNA
SCHEMBL19698852 0.72 MAPT (0.47) GRM5NSD2ALDH1A1EGFRLMNA
SCHEMBL10368854 0.70 HTR2A (0.34) ALDH1A1LMNAMAPTMAPK1TDP1
SCHEMBL1832190 0.69 SLC6A2 (0.40) GRM5LMNAMAPK1CNR2
SCHEMBL1932914 0.67 ABL1 (0.50) NSD2ALDH1A1EGFRLMNAMAPT
SCHEMBL29433183 0.66 ALDH1A1 (0.45) GRM5NSD2ALDH1A1EGFRLMNA
SCHEMBL1254512 0.66 ALDH1A1 (0.45) GRM5NSD2ALDH1A1EGFRLMNA
SCHEMBL1376447 0.66 ALDH1A1 (0.35) GRM5NSD2ALDH1A1EGFRLMNA
SCHEMBL27337998 0.65 ALDH1A1 (0.41) NSD2ALDH1A1EGFRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554392-B1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME MITSUBISHI PAPER MILLS LTD (JP) 2016-05-11 EP disclosed
US-8980791-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 EP disclosed
US-8623785-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2014-01-07 US disclosed
US-20140005046-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2014-01-02 US disclosed
US-8598075-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2013-12-03 US disclosed
US-8410019-B2 Modifying agent for coating composition for producing protective layer in thermosensitive recording medium, coating composition for protective layer in thermosensitive recording medium, and thermosensitive recording medium using the same DIC CORPORATION (JP) 2013-04-02 US disclosed
US-20130053240-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2013-02-28 US disclosed
EP-2554392-A1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME Mitsubishi Paper Mills Limited (JP) 2013-02-06 EP disclosed
US-20120329646-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2012-12-27 US disclosed
US-20030070339-A1 Rewritable thermal label of a non-contact type and method for using the label LINTEC CORPORATION (JP) 2003-04-17 US disclosed
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed
EP-0754564-B1 Heat sensitive recording material and recording method. MITSUBISHI PAPER MILLS LTD (JP) 2000-03-01 EP disclosed
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
US-5876898-A MULTICOLOR RECORDING OF HIGH CONTRAST MITSUBISHI PAPER MILLS LIMITED (JP) 1999-03-02 US disclosed
US-5817599-A COLORLESS DYE PRECURSOR AND REVERSIBLE COLOR DEVELOPER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-10-06 US disclosed
EP-0574879-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1997-05-02 EP disclosed
EP-0754564-A2 Heat sensitive recording material and recording method using the same MITSUBISHI PAPER MILLS, LTD. (JP) 1997-01-22 EP disclosed
US-5395815-A Phenolic compound electron acceptor; images; contrast; stability MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-07 US disclosed
EP-0574879-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1993-12-22 EP disclosed