Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764463 | 0.81 | FASN (0.47) | MEN1KMT2ASLC5A1SLC5A2GAA | |
| SCHEMBL1728212 | 0.80 | SLC5A1 (0.52) | MAOBSLC5A1SLC5A2GAAMAPT | |
| SCHEMBL658101 | 0.79 | MAOB (0.61) | MAOBMEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL30141054 | 0.79 | MAOB (0.61) | MAOBMEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL23422279 | 0.78 | MEN1 (0.49) | MAOBMEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL29565658 | 0.78 | MEN1 (0.49) | MAOBMEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL4273295 | 0.77 | FFAR1 (0.60) | MEN1KMT2ASLC5A1SLC5A2GAA | |
| SCHEMBL13764461 | 0.75 | SLC5A1 (0.45) | MAOBMEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL14181066 | 0.75 | MAOB (0.68) | MAOBMEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL21275494 | 0.74 | CYP3A4 (0.49) | MAOBMEN1KMT2ASLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |