Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764468 | 0.86 | SLC5A1 (0.56) | SLC5A1SLC5A2MEN1KMT2APDE4A | |
| SCHEMBL11739144 | 0.78 | MAOB (0.59) | MEN1KMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL13764460 | 0.75 | MAOB (0.47) | SLC5A1SLC5A2MEN1KMT2AMAOB | |
| SCHEMBL2951462 | 0.74 | MEN1 (0.65) | MEN1KMT2AMAOB | |
| SCHEMBL658101 | 0.74 | MAOB (0.61) | SLC5A1SLC5A2MEN1KMT2AMAOB | |
| SCHEMBL30141054 | 0.74 | MAOB (0.61) | SLC5A1SLC5A2MEN1KMT2AMAOB | |
| SCHEMBL10610437 | 0.74 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10610432 | 0.74 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL1727983 | 0.73 | SLC5A1 (0.72) | SLC5A1SLC5A2MEN1KMT2APDE4A | |
| SCHEMBL1727986 | 0.73 | SLC5A1 (0.72) | SLC5A1SLC5A2MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |