Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998793 | 1.00 | MEN1 (0.36) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL3998788 | 1.00 | MEN1 (0.36) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL3998019 | 0.85 | KMT2A (0.38) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL3998015 | 0.85 | KMT2A (0.38) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL13764887 | 0.82 | LMNA (0.39) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL4005388 | 0.82 | LMNA (0.39) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL4005382 | 0.82 | LMNA (0.39) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL4299266 | 0.80 | KMT2A (0.35) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL4299268 | 0.80 | KMT2A (0.35) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL4299269 | 0.80 | KMT2A (0.35) | MEN1KMT2APOLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563888-B2 | Process for the preparation of diphenyl azetidinone derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-07-21 | — | — | US | disclosed |
| US-20070149501-A1 | PROCESS FOR THE PREPARATION OF DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149501-A1 | PROCESS FOR THE PREPARATION OF DIPHENYL AZETIDINONE DERIVATIVES | CYP46A1, APOB, DHCR7 | MEN1 1200/4885KMT2A 1869/4885POLB 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.