Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529777 | 0.88 | ACACB (0.41) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13530365 | 0.85 | ACACB (0.42) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13529626 | 0.84 | ALDH1A1 (0.37) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13529258 | 0.84 | ALDH1A1 (0.37) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL3176231 | 0.81 | ACACB (0.39) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13530225 | 0.81 | ALDH1A1 (0.40) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13530488 | 0.80 | RXRA (0.47) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13529498 | 0.80 | ALDH1A1 (0.44) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL3168861 | 0.78 | ALDH1A1 (0.40) | ACACBALDH1A1CYP1A2TSHRCYP3A4 | |
| SCHEMBL13529628 | 0.78 | ALDH1A1 (0.40) | ACACBALDH1A1CYP1A2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562161-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2009094442-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-07-30 | — | — | WO | disclosed |