Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530322 | 0.93 | MAOB (0.40) | MAOBACACBFFAR1GRM5MAOA | |
| SCHEMBL13765145 | 0.90 | BTK (0.37) | MAOBFFAR1 | |
| SCHEMBL13765098 | 0.89 | CYP1A2 (0.41) | — | |
| SCHEMBL13765102 | 0.87 | ALDH1A1 (0.39) | MAOBACACBGRM5PIK3CAPSEN1 | |
| SCHEMBL13529480 | 0.82 | NPSR1 (0.43) | — | |
| SCHEMBL13530349 | 0.80 | FFAR1 (0.41) | MAOBFFAR1MAOASGMS2MRGPRX4 | |
| SCHEMBL3189376 | 0.79 | ALDH1A1 (0.39) | MAOBACACBGRM5PIK3CAPSEN1 | |
| SCHEMBL13529883 | 0.79 | ACACB (0.42) | MAOBACACBFFAR1PIK3CAMMP1 | |
| SCHEMBL13530326 | 0.79 | MAOB (0.48) | MAOBACACBFFAR1MAOAPIK3CA | |
| SCHEMBL13764996 | 0.79 | PARP14 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094442-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-07-30 | — | — | WO | disclosed |