Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 8/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.34 |
| ▸ | CDK9 | P50750 | 5/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765017 | 0.90 | MAOB (0.42) | MAOBFFAR1 | |
| SCHEMBL13765098 | 0.88 | CYP1A2 (0.41) | — | |
| SCHEMBL13765102 | 0.83 | ALDH1A1 (0.39) | BTKMAOB | |
| SCHEMBL13530322 | 0.83 | MAOB (0.40) | MAOBFFAR1 | |
| SCHEMBL13529480 | 0.80 | NPSR1 (0.43) | — | |
| SCHEMBL14734485 | 0.79 | SYK (0.39) | SYKMAOBRXRAGRIN1GRIN2B | |
| SCHEMBL13530349 | 0.78 | FFAR1 (0.41) | SYKMAOBFFAR1 | |
| SCHEMBL13764996 | 0.77 | PARP14 (0.39) | — | |
| SCHEMBL14734484 | 0.77 | ROCK2 (0.41) | BTKSYKAURKBFFAR1THRA | |
| SCHEMBL3189376 | 0.76 | ALDH1A1 (0.39) | BTKMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094442-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-07-30 | — | — | WO | disclosed |