SCHEMBL13765341

SCHEMBL13765341

C/C=C(\C)COC(=O)Oc1ncc(F)c(/N=C/N(C)C)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3173756 0.86 KDM4E (0.35) CYP1A2CYP2C19
SCHEMBL3173760 0.86 KDM4E (0.35) CYP1A2CYP2C19
SCHEMBL13530493 0.84 CA2 (0.31)
SCHEMBL13530345 0.83 ALDH1A1 (0.30)
SCHEMBL13530422 0.83 ALDH1A1 (0.34)
SCHEMBL13529970 0.83 ALDH1A1 (0.30)
SCHEMBL13530175 0.83 ALDH1A1 (0.33) CYP1A2CYP2C19
SCHEMBL13530327 0.83 KDM4E (0.33)
SCHEMBL13529467 0.81 HSD17B10 (0.38) CYP1A2CYP2C19
SCHEMBL17004446 0.80 CYP1A2 (0.36) CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009094442-A2 5-FLUORO PYRIMIDINE DERIVATIVES DOW AGROSCIENCES LLC (US) 2009-07-30 WO disclosed